ENCH482-24S1 (C) Semester One 2024

Bioprocess Engineering 2

15 points

Details:
Start Date: Monday, 19 February 2024
End Date: Sunday, 23 June 2024
Withdrawal Dates
Last Day to withdraw from this course:
  • Without financial penalty (full fee refund): Sunday, 3 March 2024
  • Without academic penalty (including no fee refund): Sunday, 12 May 2024

Description

This course focuses on the priciples of bioseparation processes: cellular fractionation, filtration, chromatography, electrophoresis, immunoaffinity techniques and their application to various types of biomolecules. It includes a hands-on laboratory to separate a target microbially-produced protein by chromatography and assay the purity by electrophoresis.

• Biomolecular properties (6 lectures)
• Cellular fractionation and cell disruption techniques (5 lectures)
• Liquid chromatography separations (7 lectures)
• Electrophoresis (6 lectures)
• Immunoaffinity methods (4 lectures)
• Mammalian cell separations (2 lectures)
• Bioprocess case studies (5 lectures)

Learning Outcomes

  • At the end of this course, students will:

  • Have an overview of the separation and purification of biological materials.

  • Understand how to exploit biological molecular properties for their separation.

  • Obtain an overview of bioseparation principles to develop bioseparation strategies for complex biological mixtures.

  • Understand and apply the principles of process scale-up in bioseparation processes.

  • Apply optimization and scale-up principles to design or improve a bioseparation process.

Prerequisites

Timetable 2024

Students must attend one activity from each section.

Lecture A
Activity Day Time Location Weeks
01 Wednesday 16:00 - 17:00 Jack Erskine 441
19 Feb - 31 Mar
22 Apr - 2 Jun
Lecture B
Activity Day Time Location Weeks
01 Friday 10:00 - 11:00 Jack Erskine 441
19 Feb - 24 Mar
22 Apr - 2 Jun
Lecture C
Activity Day Time Location Weeks
01 Tuesday 14:00 - 15:00 Ernest Rutherford 460
19 Feb - 31 Mar
22 Apr - 2 Jun
Lab A
Activity Day Time Location Weeks
02 Thursday 10:00 - 13:00 CAPE 113 Teaching Lab
25 Mar - 31 Mar
03 Monday 10:00 - 13:00 CAPE 113 Teaching Lab
25 Mar - 31 Mar
Lab B
Activity Day Time Location Weeks
01 Thursday 10:00 - 13:00 CAPE 113 Teaching Lab
6 May - 19 May

Examination and Formal Tests

Test A
Activity Day Time Location Weeks
01 Friday 19:00 - 21:00 Jack Erskine 031 Lecture Theatre
29 Apr - 5 May

Course Coordinator / Lecturer

Rachael Wood

Lecturer

Carlo Carere

Assessment

Assessment Due Date Percentage 
Final Exam 40%
Assignment 1 22 Mar 2024 10%
Assignment 2 26 Apr 2024 10%
Mid term test 03 May 2024 25%
Assignment 3 17 May 2024 5%
Lab Report 31 May 2024 10%


36 lectures plus 2 labs.

Students are expected to spend approximately 2 hours per week reviewing lecture content and preparing for labs, and an additional 10 hours per assignment.

Textbooks / Resources

There are no assigned textbooks for this course. Textbooks you may find interesting/useful include:

Bioprocess Engineering Principles (Pauline Doran)

Chemical Engineering Design (Sinnott Towler)

Bioprocess Engineering: Basic Concepts (Michael Schuler)

Notes

All information about academic policies (e.g. special consideration, dishonest practice) can be found on the ENCH-Undergraduate LEARN page .

This course is required to complete the Bioprocess Engineering minor in Chemical and Process Engineering.

Prerequisites: ENGR407

Indicative Fees

Domestic fee $1,197.00

International fee $6,000.00

* All fees are inclusive of NZ GST or any equivalent overseas tax, and do not include any programme level discount or additional course-related expenses.

For further information see Chemical and Process Engineering .

All ENCH482 Occurrences

  • ENCH482-24S1 (C) Semester One 2024